:where(.disease-shell){--c-ink:#414042;--c-orange:var(--color-brand-guideline,#f37021);--c-orange-d:#d85c13;--c-bg:#fff;--c-bg-soft:#f7f7f8;--c-bg-tint:#fff6f0;--c-border:#e6e6e8;--c-muted:#6b6b6e;--c-link:#c45612;--c-dark:#2c2c2e;--r-sm:6px;--r-md:12px;--r-lg:20px;--shadow-sm:0 1px 2px #1414160a, 0 1px 3px #1414160f;--container:1200px;--article:720px;--aside:320px;--gap:40px;font-family:var(--font-sans);color:var(--c-ink);-webkit-font-smoothing:antialiased;text-rendering:optimizelegibility;scroll-behavior:smooth;font-size:17px;line-height:1.65}:where(.disease-shell) .disease-container{max-width:var(--container);margin:0 auto;padding:0 20px}@media (min-width:480px){:where(.disease-shell) .disease-container{padding:0 24px}}@media (min-width:768px){:where(.disease-shell) .disease-container{padding:0 32px}}:where(.disease-shell) .disease-layout{grid-template-columns:1fr;gap:32px;padding:8px 0 64px;display:grid}@media (min-width:1024px){:where(.disease-shell) .disease-layout{grid-template-columns:1fr var(--aside);gap:var(--gap);padding:16px 0 96px}}:where(.disease-shell) .disease-main{min-width:0}@media (min-width:1024px){:where(.disease-shell) .disease-inner{max-width:var(--article)}}:where(.disease-shell) .disease-sidebar{display:none}@media (min-width:1024px){:where(.disease-shell) .disease-sidebar{top:calc(var(--header-h,64px) + 16px);scrollbar-width:thin;scrollbar-color:#0000001f transparent;align-self:start;height:fit-content;max-height:calc(100vh - 100px);display:block;position:sticky;overflow-y:auto}:where(.disease-shell) .disease-sidebar::-webkit-scrollbar{width:4px}:where(.disease-shell) .disease-sidebar::-webkit-scrollbar-thumb{background:#0000001f;border-radius:4px}}:where(.disease-shell) .disease-sidebar-block{border:1px solid var(--c-border);border-radius:var(--r-md);background:#fff;margin-bottom:18px;padding:20px}:where(.disease-shell) 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.disease-sidebar-cta-btn{border-radius:var(--r-sm);cursor:pointer;background:var(--c-orange);color:#fff;border:none;justify-content:center;align-items:center;padding:11px 18px;font-family:inherit;font-size:14px;font-weight:700;text-decoration:none;transition:background .2s,transform .15s;display:inline-flex}:where(.disease-shell) .disease-sidebar-cta-btn:hover{background:var(--c-orange-d);transform:translateY(-1px)}:where(.disease-shell) .disease-eyebrow{letter-spacing:1.6px;color:var(--c-orange);text-transform:uppercase;align-items:center;gap:8px;margin:8px 0 16px;font-size:12px;font-weight:700;display:inline-flex}:where(.disease-shell) .disease-eyebrow:before{content:"";background:var(--c-orange);width:24px;height:2px}:where(.disease-shell) .disease-h1{letter-spacing:-.02em;color:var(--c-ink);margin:0 0 20px;font-size:clamp(28px,5.4vw,44px);font-weight:700;line-height:1.18}:where(.disease-shell) .disease-author-mobile{background:var(--c-bg-tint);border-radius:var(--r-md);border:1px solid #f3702126;margin:0 0 20px;padding:14px 16px;display:block}:where(.disease-shell) .disease-author-mobile .a-author{background:0 0;border:none;grid-template-columns:40px 1fr;gap:10px;margin:0;padding:0}:where(.disease-shell) .disease-author-mobile .a-author-photo{width:40px;height:40px}:where(.disease-shell) .disease-author-mobile .a-author-name{font-size:13px}:where(.disease-shell) .disease-author-mobile .a-author-role{font-size:11px}@media (min-width:1024px){:where(.disease-shell) .disease-author-mobile{display:none}}:where(.disease-shell) .disease-meta-bar{border-top:1px solid var(--c-border);border-bottom:1px solid var(--c-border);color:var(--c-muted);flex-wrap:wrap;align-items:center;gap:10px 16px;margin:6px 0 28px;padding:14px 0 18px;font-size:14px;display:flex}:where(.disease-shell) .disease-detail-badge{white-space:nowrap;border-radius:1rem;padding:.3rem .7rem;font-size:.8rem;font-weight:700}.dbadge--d{color:#b91c1c;background:#fee2e2}.dbadge--v{color:#92400e;background:#fef3c7}.dbadge--b{color:#065f46;background:#d1fae5}.dbadge--g{color:#1e40af;background:#dbeafe}.dbadge--a{color:#047857;background:#d1fae5}.dbadge--default{color:#4b5563;background:#f3f4f6}:where(.disease-shell) .disease-article-ref{color:var(--c-ink);font-weight:600}:where(.disease-shell) .disease-synonyms{background:var(--c-bg-soft);border:1px solid var(--c-border);border-radius:var(--r-md);color:var(--c-muted);margin:0 0 24px;padding:14px 18px;font-size:15px;line-height:1.5}:where(.disease-shell) .disease-synonyms strong{color:var(--c-ink)}:where(.disease-shell) .disease-description{background:var(--c-bg-soft);border:1px solid var(--c-border);border-radius:var(--r-md);color:#3a3a3c;margin:0 0 28px;padding:20px 22px 20px 24px;font-size:15px;line-height:1.7;position:relative;overflow:hidden}:where(.disease-shell) .disease-description:before{content:"";background:var(--c-orange);width:4px;position:absolute;top:0;bottom:0;left:0}:where(.disease-shell) .disease-description__title{letter-spacing:.5px;text-transform:uppercase;color:var(--c-orange);margin:0 0 12px;font-size:13px;font-weight:700}:where(.disease-shell) .disease-comment{border-radius:var(--r-md);background:#f0f4ff;border:1px solid #d4dff7;margin:0 0 32px;padding:24px 24px 24px 28px;position:relative;overflow:hidden}:where(.disease-shell) .disease-comment:before{content:"";background:#4a6cf7;width:4px;position:absolute;top:0;bottom:0;left:0}:where(.disease-shell) .disease-comment__header{align-items:center;gap:10px;margin:0 0 14px;display:flex}:where(.disease-shell) .disease-comment__icon{color:#4a6cf7;flex-shrink:0}:where(.disease-shell) .disease-comment__title{color:#1e293b;margin:0;font-size:18px;font-weight:700}:where(.disease-shell) .disease-comment__body{color:#334155;font-size:15px;line-height:1.7}:where(.disease-shell) .disease-comment__body p{margin:0 0 8px}:where(.disease-shell) .disease-comment__body p:last-child{margin-bottom:0}@media (max-width:479px){:where(.disease-shell) .disease-comment{padding:18px 16px 18px 20px}}:where(.disease-shell) .disease-consequence{white-space:nowrap;border-radius:.75rem;padding:.25rem .65rem;font-size:.75rem;font-weight:600;line-height:1.4}.consequence--d{color:#991b1b;background:#fecaca}.consequence--v{color:#854d0e;background:#fef9c3}.consequence--g{color:#1e3a8a;background:#bfdbfe}.consequence--b,.consequence--a{color:#14532d;background:#bbf7d0}@media (max-width:479px){:where(.disease-shell) .disease-meta-bar{flex-direction:column;align-items:flex-start;gap:8px}}:where(.disease-shell) .disease-examinations{background:var(--c-bg-soft);border:1px solid var(--c-border);border-radius:var(--r-lg);margin:0 0 36px;padding:28px 24px}:where(.disease-shell) .disease-examinations__title{color:var(--c-ink);margin:0 0 4px;font-size:20px;font-weight:700}:where(.disease-shell) .disease-examinations__subtitle{color:var(--c-muted);margin:0 0 20px;font-size:14px}:where(.disease-shell) .disease-examinations__list{flex-direction:column;gap:0;margin:0;padding:0;list-style:none;display:flex;position:relative}:where(.disease-shell) .disease-examinations__list:before{content:"";background:var(--c-border);width:2px;position:absolute;top:22px;bottom:22px;left:18px}:where(.disease-shell) .disease-examinations__item{align-items:flex-start;gap:16px;padding:14px 0;display:flex;position:relative}:where(.disease-shell) .disease-examinations__num{background:var(--c-orange);color:#fff;z-index:1;border-radius:50%;flex-shrink:0;justify-content:center;align-items:center;width:36px;height:36px;font-size:14px;font-weight:700;display:flex;position:relative;box-shadow:0 2px 6px #f3702140}:where(.disease-shell) .disease-examinations__text{color:var(--c-ink);padding-top:6px;font-size:15px;line-height:1.6}@media (max-width:479px){:where(.disease-shell) .disease-examinations{padding:20px 16px}:where(.disease-shell) .disease-examinations__list:before{left:15px}:where(.disease-shell) .disease-examinations__num{width:30px;height:30px;font-size:12px}:where(.disease-shell) .disease-examinations__item{gap:12px}}:where(.disease-shell) .disease-cta-inline{background:var(--c-orange);border-radius:var(--r-lg);color:#fff;text-align:center;background-image:radial-gradient(circle at 100% 0,#ffffff2e 0%,#0000 50%),radial-gradient(circle at 0 100%,#00000014 0%,#0000 50%);margin:36px 0;padding:28px 24px}:where(.disease-shell) .disease-cta-inline h3{margin:0 0 8px;font-size:20px;font-weight:700}:where(.disease-shell) .disease-cta-inline p{opacity:.92;margin:0 0 18px;font-size:15px;line-height:1.5}:where(.disease-shell) .disease-cta-btn{border-radius:var(--r-sm);cursor:pointer;color:var(--c-orange);background:#fff;border:none;justify-content:center;align-items:center;padding:12px 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.a-author-role{color:var(--c-muted);margin:0 0 6px;font-size:13px;line-height:1.4}:where(.disease-shell) .a-author-detail-btn{color:var(--c-link);cursor:pointer;background:0 0;border:none;align-items:center;gap:5px;margin-bottom:4px;padding:0;font-family:inherit;font-size:13px;font-weight:500;text-decoration:none;display:inline-flex}:where(.disease-shell) .a-author-detail-btn svg{color:var(--c-orange);opacity:.7;flex-shrink:0}:where(.disease-shell) .a-author-detail-btn:hover{color:var(--c-orange-d);text-decoration:underline}:where(.disease-shell) .a-author-detail-btn:hover svg{opacity:1}.a-author-modal-overlay{z-index:2100;background:#00000080;justify-content:center;align-items:center;padding:24px;animation:.2s a-modal-fade-in;display:flex;position:fixed;inset:0}@keyframes a-modal-fade-in{0%{opacity:0}to{opacity:1}}.a-author-modal{overscroll-behavior:contain;background:#fff;border-radius:16px;width:100%;max-width:520px;max-height:calc(100vh - 48px);padding:32px;animation:.25s 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img,.a-author-modal-photo svg{object-fit:cover;width:100%;height:100%}.a-author-modal-name{color:#414042;margin:0 0 4px;font-size:22px;font-weight:700;line-height:1.25}.a-author-modal-role{color:#6b6b6e;margin:0;font-size:14px;line-height:1.4}.a-author-modal-body{flex-direction:column;gap:18px;display:flex}.a-author-modal-section-title{letter-spacing:1.4px;text-transform:uppercase;color:#f37021;margin:0 0 8px;font-size:11px;font-weight:700}.a-author-modal-text{color:#414042;margin:0;font-size:15px;line-height:1.6}.a-author-modal-details{flex-direction:column;gap:8px;display:flex}.a-author-modal-detail{color:#535357;align-items:center;gap:8px;font-size:14px;display:flex}.a-author-modal-detail svg{color:#f37021;opacity:.8;flex-shrink:0}.a-author-modal-detail strong{color:#414042;font-weight:600}.a-author-modal-tags{flex-wrap:wrap;gap:6px;display:flex}.a-author-modal-tag{color:#c45612;background:#fff6f0;border:1px solid #f3702133;border-radius:100px;padding:5px 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